1/10/2023 0 Comments White pupil![]() Many conditions cause leukocoria including cataract, retinal detachment, retinopathy of prematurity, intraocular infection (endophthalmitis), retinal vascular abnormality (such as Coat’s Disease), and intraocular tumor ( retinoblastoma). Dilating eye drops are generally used to enlarge the pupil which enables a more thorough examination. Ophthalmologists utilize an ophthalmoscope to directly visualize the interior of the eye. HOW DOES AN OPHTHALMOLOGIST DETECT LEUKOCORIA? Pediatricians will refer patients with “abnormal red reflex” on their exam for a more thorough exam by a pediatric ophthalmologist. This occurs because of abnormal reflection or blockage of light coming out of the eye. The red reflex is either absent or white with leukocoria. An example is a camera in which the flash is mounted very close to the lens resulting in photographs with red pupillary reflexes. The “red reflex” is most easily seen when the observer's line of sight is aligned with the light source into the eye. The light is reddish orange, reflecting the color of normal retina. A small amount of light, however, is reflected by the retina back out of the eye through the pupil. When light enters the eye through the pupil, the retina absorbs most of the light. Sometimes leukocoria is detected from photographs using a flash when one pupil has an abnormal or "white reflex" compared to the other eye having a normal "red reflex." Lastly, a routine pediatrician exam can catch leukocoria, specifically when they look into the eyes with a special instrument called an ophthalmoscope. In other situations, the pupil may appear white only in certain circumstances such as when the pupil becomes larger in a darkened room or when the child looks a particular direction. ![]() In more obvious cases a white pupil may be detected simply by looking at a child’s eye in good lighting. ![]() 1: Leukocoria occurs when the pupil is white rather than the usual black. Leukocoria literally means "white pupil." It occurs when the pupil (the round hole in the colored part of the eye) is white rather than the usual black.
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